中心负责人朱楚洪教授为 十三五 国家重点研发计划首席科学家、国家杰青获得者,所领导的学科为第三军医大学国家重点培育学科,实验室为国家发改委组织工程国家地方联合工程实验室血管组织工程中心,国家发改委血管植入物国家地方联合工程实验室人工血管中心。课题组基础研究与应用研究并重,前期研发了新型生物人工血管、生物人工角膜、糖尿病促愈合生物敷料、心肌修复水凝胶等系列产品,在Acs Nano,Advanced Science、Biomaterials、Arterioscler Thromb Vasc Biol等杂志发表系列论著。
研究方向:
1. 血管化复杂组织器官构建及新型医疗器械研发
2. 药物缓释及工程化改造的细胞治疗新技术开发
3. 材料学与再生医学研究
4. 神经、免疫与再生医学研究
近三年代表性论著:
1.Huo D, LiuG, Li,Y, WangY, Guan G,Yang M
,Wei K, Yang J,Zeng L,Li G, Zeng W*,Zhu C*. Construction of Antithrombotic
Tissue-Engineered Blood Vessel via Reduced Graphene Oxide based Dual-Enzyme
Biomimetic Cascade. ACS Nano. 2017, 11(11):10964-973. (IF: 13.709)
2.
Li Y, Wan S, Liu G, Wang C, Huo D, Li G, YangM, Wang Y, Guan G, Ding N, Liu F,
Zeng W*,Zhu C*.Netrin-1 Promotes Inflammation Resolution to
AchieveEndothelialization of Small-diameter Tissue Engineering Blood Vessels
byImproving Endothelial Progenitor Cells Function in Situ. Advanced Science. 2017;4(12):1700278. (IF:12.441)
3.Liu G, Li L, Huo D, Li Y, Wu Y, Zeng
L,Cheng P, Xing M, Zeng W, Zhu C*.AVEGF delivery system targeting MI improves
angiogenesis an d cardiacfunctionbased on the tropism of MSCs an d layer-by-layer
self-assembly. Biomaterials 2017;127:117-131.(IF: 8.806)
4.Cheng P, Zeng W, Li L, Huo D, Zeng L,
Tan J,Zhou J, Sun J, Liu G, Li Y, Guan G, Wang Y, Zhu C*. PLGA-PNIPAM
microspheres loaded with the gastrointestinalnutrient NaB ameliorate cardiac
dysfunction by activating Sirt3 in acutemyocardial infarction. Advanced
Science.2016;3(12):1600254.(IF:12.441)
5.Chen W, Zeng W, Sun J, YangM, Li L,
Zhou J, Wu Y, Sun J, Liu G, Tang R, Tan J,Zhu C*.Construction of an
Aptamer-SiRNA Chimeras Modified Tissue-Engineered Blood Vessel for Cell
Type-Specific Capture an d Delivery.ACS Nano. 2015;9(6):6069-76. (IF:13.709)